Question
How many eggs have been used for nuclear transfer under Human Fertilisation and Embryology Authority research licence R0152; how many embryonic stem cell lines have been so derived; and how this compares to the stipulation in licences issued to Sydney IVF Ltd (309712, 309713 and 309714) that no more eggs may be used if no embryonic stem cell lines have been established after using 1,600 eggs.
Answer
The Human Fertilisation and Embryology Authority (HFEA) does not set limits on the kinds of eggs which can be donated to research. Women donating eggs to research can either be non-patients or women who are patients receiving in vitro fertilisation treatment. They donate eggs which are suitable for fertilisation. The HFEA reviewed its policies in this area in 2007 and came to the view that donation to research through an egg-sharing arrangement was appropriate, subject to certain safeguards to protect the donor. The report of this policy review can be found at: www.hfea.gov.uk/en/1417.htm. The latest inspection report for research licence R0152 is available on the HFEA's website at: www.hfea.gov.uk/en/1368.html#17. The inspection report sets out the numbers of fresh and failed-to-fertilise eggs that were used in the project during 2007 and the expected numbers for 2008. During 2007, 56 failed-to-fertilise eggs were used and 19 fresh eggs. It is expected that during 2008, the project will use 200 failed-to-fertilise eggs and 400 fresh eggs. No embryonic stem cell lines have so far been derived. The HFEA does not set a limit on the number of eggs which can be used in embryonic stem cell research, although its licence committees monitor the efficiency of the process used and the number of eggs used in them. We cannot comment on the stipulations put on licences granted to the Sydney IVF Ltd.